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Pol. Merkur. Lek (Pol. Med. J.), 2016, XLI/246: 296-302
Title: Pancreatic cancer microenvironment
Authors: Dąbkowski K, Bogacka B, Tarnowski M, Starzyńska T.
Title: Pancreatic cancer microenvironment
Authors: Dąbkowski K, Bogacka B, Tarnowski M, Starzyńska T.
SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN POLISH.
Pancreatic cancer microenvironment
Dąbkowski K1, Bogacka B1, Tarnowski M2, Starzyńska T1.
Pomeranian Medical University of Szczecin, Poland: 1Department of Gastroenterology; 2Department of Physiology
Pancreatic cancer remains one of the deadliest solid tumors in humans and an unsolved problem of today’s medicine. Experimental studies reveal that the heterogeneous and complex pancreatic cancer microenvironment is responsible, not only for cancer growth, spread, development of metastases, but also for cancer recurrence and chemotherapy resistance. Chemotherapy affecting the cancer stroma is still under clinical and experimental research and remains hope for cure of pancreatic cancer. We present the cancer microenvironment characteristics and summary of experimental studies with use of agents affecting pancreatic cancer stroma.
Key words: pancreatic cancer, tumor microenvironment, pancreatic stellate cells
Pol Med J, 2016; XLI (246); 296–302
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