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Pol. Merkur. Lek (Pol. Med. J.), 2019, XLVII/281: 167-169 Maximize

Pol. Merkur. Lek (Pol. Med. J.), 2019, XLVII/281: 167-169

Title: Red-cell distribution width is associated with higher risk of vascular complications after carotid thromboendartherectomy 

Authors: Bojakowski K, Religa R, Andziak P, Gaciong Z. 

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SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN ENGLISH.

Red-cell distribution width is associated with higher risk of vascular complications after carotid thromboendartherectomy

Bojakowski K1, Religa R2, Andziak P1, Gaciong Z3.

1Department of General and Vascular Surgery, Central Clinical Hospital of Ministry of Internal Affairs, Warsaw, Poland; 2Department of Medicine, Solna, Karolinska Institute, Stockholm, Sweden; 3Department of Internal Medicine, Hypertension and Vascular Diseases, Medical University of Warsaw, Poland

Red Cell Distribution Width (RDW) is associated with increased morbidity and mortality in subjects with clinically manifested vascular diseases as well as predicts cardiovascular incidents and different types of cancer in a healthy population.
The aim of the study
was to evaluate relationship between clinical outcomes in patients after carotid thromboendarterectomy and initial RDW values.
Material and methods
. Data from 115 subsequent patients who underwent carotid thromboendartherectomy (TEA) were retrospectively analyzed. All patients had complete blood count measured including RDW and were observed for 18 months post-operatively. On each visit doppler ultrasound of carotid arteries was performed to evaluate the development of restenosis and progression of atherosclerosis.
Results
. Primary endpoint defined as cardiovascular death, new cerebrovascular incidents (stroke or TIA), any new revascularization procedure (carotid, coronary or peripheral) and restenosis of the operated artery occurred in 28 patients. They differed from subjects with uneventful course with increased prevalence of previous cerebrovascular incidents (75.0% and 42.5%, respectively; p=0.0028) and higher RDW values (14,37±1.55% and 13.77±0.96%, p=0.0155).
Conclusions
. In patients with high risk for cerebrovascular incidents, RDW identifies population at increasingly high probability of vascular complications which should be subjected to intensive therapeutic regimen.

Key words: red cell distribution width, thromboendarterectomy, restenosis, cardiovascular complications

Pol Med J, 2019; XLVII (281); 167–169