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Pol. Merkur. Lek (Pol. Med. J.), 2020, XLVIII/285: 166-169 Maximize

Pol. Merkur. Lek (Pol. Med. J.), 2020, XLVIII/285: 166-169

Title: Is vitamin D concentration an indicator of the severity of atopic dermatitis and chronic spontaneous urticaria in adults? 

Authors: Jaworek AK, Obtułowicz A, Hałubiec P, Krzysztofik E, Wojas-Pelc A. 

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SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN ENGLISH.

Is vitamin D concentration an indicator of the severity of atopic dermatitis and chronic spontaneous urticaria in adults?

Jaworek AK1, Obtułowicz A1, Hałubiec P2, Krzysztofik E2, Wojas-Pelc A1.

1Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland; 2Student Scientific Group of Dermatology, Jagiellonian University Medical College, Krakow, Poland

Atopic dermatitis (AD) and chronic spontaneous urticaria (CSU) are common chronic and recurrent dermatoses. The role of vitamin D in the immunological processes, including the development of inflammation, has been the subject of numerous studies. The feasible measurement of vitamin D serum concentration and possibly supplementation necessitates the assessment of its impact on the clinical severity of mentioned diseases.
The aim of the study
was to determine the relationship between blood serum vitamin D concentration and the severity of clinical symptoms in the group of adults suffering from AD or CSU.
Material and methods
. The study was conducted in 2018 on groups of patients suffering from AD or CSU. Serum vitamin D concentration was determined by electrochemiluminescence assay. Student’s t-test was adopted to compare vitamin D levels between groups. Spearman’s rank correlation coefficient was used to assess the correlation between vitamin D concentration and the severity of AD (according to the SCORAD scale) and CSU (according to the UAS 7 scale).
Results
. There was not found any statistically significant relationship between the severity of skin lesions scores in the course of AD and CSU and serum vitamin D concentration.
Conclusions
. The results of conducted study indicate that the assessment of vitamin D concentration does not allow to predict the clinical course of AD and CSU. The definitive determination of the role of vitamin D in the management of patients with discussed disease entities requires further research.

Key words: vitamin D, atopic dermatitis, chronic spontaneous urticaria, SCORAD, UAS 7

Pol Med J, 2020; XLVIII (285); 166–169