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Pol. Merkur. Lek (Pol. Med. J.), 2016, XLI/244: 192-195 Maximize

Pol. Merkur. Lek (Pol. Med. J.), 2016, XLI/244: 192-195

Title: Ocular toxocariasis in a boy with idiopathic nephrotic syndrome – a case report 

Author: Antonowicz A, Skrzypczyk P, Kępa B, Pańczyk-Tomaszewska M. 

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Ocular toxocariasis in a boy with idiopathic nephrotic syndrome – a case report

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Antonowicz A1, Skrzypczyk P1, Kępa B2, Pańczyk-Tomaszewska M1.

1Department of Pediatrics and Nephrology, Medical University of Warsaw, Poland; 2Department of Ophthalmology, Children’s Memorial Health Institute of Warsaw, Poland

Toxocariasis is a common zoonosis caused by infection with Toxocara canis or cati larvae. Ocular toxocariasis is one of the forms of infestation found in 1/1,000 – 1/10,000 children. Children with idiopathic nephrotic syndrome (INS) are at high risk of infections, also parasitic infestations, which can, in turn, cause relapses of the disease
A case report
. We present a case of a 6-year-old boy with steroiddependent nephrotic syndrome. The disease started at age of 2, the boy had 9 relapses of INS, and was treated with oral prednisone, levamisole, and cyclophosphamide. During hospitalization with Xth relapse of INS, he was screened for causes of recurrences and IgG antibodies against Toxocara were found. Fundoscopy revealed white, slightly elevated, and discoloured inflammatory lesions in right retina without inflammation in the vitreous. Ocular toxocariasis was diagnosed. The boy was treated for 7 days with albendazole in the dose of 15 mg/kg/24 h with simultaneous increase of the dose of prednisone to 1mg/kg/24 h. In control fundoscopic examinations there was no progression of ocular lesions.
Conclusion
. In children on immunosuppressive treatment with possible exposure to animals or raw meet it is advisable to take serological tests for Toxocara infestation also in the absence of clinical symptoms of parasitic infection.

Key words: ocular toxocariasis, parasitic diseases, children, idiopathic nephrotic syndrome

Pol Med J, 2016; XLI (244); 192–195