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Int. Rev. Allergol. Clin. Immunol. Family Med., 2017, XXIII/3: 097-102 Maximize

Int. Rev. Allergol. Clin. Immunol. Family Med., 2017, XXIII/3: 097-102

Title: Obesity and asthma  

Author: Płusa T. 

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01-03-2017

40,00 zł

SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN POLISH.

Obesity and asthma


Płusa T.

EMC Medical Institute SA – Department of Internal Medicine and Lung Disease, Hospital st. Anna in Piaseczno, Poland

Int Rev Allergol Clin Immunol Family Med, 2017; Vol. 23, No. 3, 097

Obesity is a complex disease, which affect manifestations of disease in the airway and produces fundamental changes in innate and adaptive immunity. Obesity is associated with innate airway reactivity, in the absence of any provocative agent, and without obvious airway inflammation. Two major phenotypes of asthma have been identified in obese patients with asthma (late-onset, non-allergic and early onset allergic). These different phenotypes of asthma in obesity will require customized treatment based on the underlying pathophysiology of the disease. Obese patients with asthma do not respond as well to glucocorticoids. Treatment trials targeting specific phenotypes of obese patients with asthma are needed.

Key words: asthma, obesity