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Pol. Merkur. Lek (Pol. Med. J.), 2020, XLVIII/286: 241-244 Maximize

Pol. Merkur. Lek (Pol. Med. J.), 2020, XLVIII/286: 241-244

Title: What difficulties can we encounter in the diagnosis of plasma cell myeloma? 

Authors: Sałek M, Rawska A, Gawęda A, Wojciechowicz J. 

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SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN ENGLISH.

What difficulties can we encounter in the diagnosis of plasma cell myeloma?


Sałek M1, Rawska A1, Gawęda A2, Wojciechowicz J2.

Medical University of Lublin, Poland: 1Students’ Scientific Group of Chair and Clinic of Maxillofacial Surgery; 2Chair and Clinic of Maxillofacial Surgery

Plasma cell myeloma is a cancer originating from plasmocytes. This disease is characterized by a bone marrow infiltration by plasmocytes, which produce monoclonal immunoglobulin or light chains of immunoglobulins (so-called M-protein) and release cytokines stimulating bone destruction. It represents 1% of all neoplasms and 10-15% of haematological neoplasms. The median age of the disease is 70 years. In imaging, PCM lesions are described as osteolytic, osteoporotic or mixed. This radiological appearance can occur in many diseases’ categories.
A case report
. A 60-year-old patient was admitted to the Department of Maxillofacial Surgery in Lublin in 2018 in order to diagnose and treat a pathological lesion of the right maxilla. Patient has been treated due to generalised PCM since 2016. CT examination of the bones indicated the presence of osteolytic lesion of the right maxilla, radiologically corresponded to the odontogenic cyst. However, because of the coexisting disease, it was impossible to make a final diagnosis at this stage of diagnostics. After additional examinations, the patient was qualified for enucleation of the lesion. The result of histopathological examination confirmed the presence of a follicular cyst.
Conclusions
. In the described case, particular attention has been paid to the differentiation of cysts with bone osteolytic defects occurring in PCM. The final diagnosis is the result of histopathological examination of the tissue material obtained during an enucleation procedure of the pathological lesion of the maxilla.

Key words: plasma cell myeloma, follicular cyst, differential diagnosis

Pol Med J, 2020; XLVIII (286); 241–244