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Pol. Merkur. Lek (Pol. Med. J.), 2013, XXXV/205: 047-050 Maximize

Pol. Merkur. Lek (Pol. Med. J.), 2013, XXXV/205: 047-050

Title: Refractory celiac disease

Authors: Iwańczak F., Iwańczak B.

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SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN POLISH.

Refractory celiac disease


Iwańczak F., Iwańczak B.

Medical University of Wrocław, Poland, 2nd Chair and Department of Pediatrics, Gastroenterology and Nutrition Refractory celiac disease is characterized by the persistence or recurrence of symptoms connected with enteropathy, presence of specific antibodies in the serum: EMA, tTG2 and DPG, and (or) intestinal villous atrophy despite strict adherence to gluten-free diet for 6 to 12 months. Correct initial diagnosis of celiac disease, exclusion of other causes of the lack of response to gluten-free diet and persistence of villous atrophy are necessary conditions of diagnosis of refractory celiac disease. Options of the treatment, depending on the patient condition are: gluten-free diet, elementary diet, parenteral nutrition, immunosuppression and biological therapy.

Key words: refractory celiac disease, diagnostics, treatment

Pol. Merk. Lek., 2013, XXXV, 205, 47