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Int. Rev. Allergol. Clin. Immunol. Family Med., 2014, XX/3: 136-139 Maximize

Int. Rev. Allergol. Clin. Immunol. Family Med., 2014, XX/3: 136-139

Title: Cytokine profile in patients treated with anti-IgE – case reports

Authors: Płusa T., Wesołowski A., Rożyńska R., Chudzicka A.

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05-03-2014

40,00 zł

SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN POLISH.

Cytokine profile in patients treated with anti-IgE – case reports

Płusa T., Wesołowski A., Rożyńska R., Chudzicka A.


Military Institute of Medicine in Warsaw, Poland, Central Clinical Hospital of the Ministry of National Defense, Department of Internal Medicine, Pneumonology and Allergology

Int. Rev. Allergol. Clin. Immunol. Family Med., 2014; Vol. 20, No. 3, 136

Patients with severe difficult asthma require special treatment. Lack of control over the course of the disease is the main indication for adoption of treatment with anti-IgE. The paper presents three patients with severe asthma who used non-standard treatment with omalizumab. The result obtained after two years of observation points to the legitimacy of such proceedings. Moreover, the full stabilization of the clinical status of patients, improvement in spirometric indices and trends in the cytokine profile support clinical results. It is suggested that the present monitoring of patients with concentrations of pro and antiinflammatory cytokines may be useful in efficacy control in severe difficult asthma.

Key words: severe difficult asthma, omalizumab, cytokines