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Int. Rev. Allergol. Clin. Immunol. Family Med., 2014, XX/3: 145-149 Maximize

Int. Rev. Allergol. Clin. Immunol. Family Med., 2014, XX/3: 145-149

Title: Asthma-COPD overlap syndrome

Author: Chudzicka A.

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07-03-2014

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SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN POLISH.

Asthma-COPD overlap syndrome

Chudzicka A.

Military Institute of Medicine in Warsaw, Poland, Central Clinical Hospital of the Ministra of National Defense, Departament of Internal Medicine, Pneumonology and Allergology

Int. Rev. Allergol. Clin. Immunol. Family Med., 2014; Vol. 20, No. 3, 145

Asthma and chronic obstructive pulmonary disease (COPD) are two of the most common airway diseases. So far, they were considered as two separate diseases. Recently, the fact, that they may coexist, is underlined, which was called asthma-COPD overlap syndrome. The part of the risk factors are common for both diseases. The definition of the overlap syndrome is controversial. Further investigations on airway remodeling and inflammatory processes may help to determine the diagnostic criteria. New mediators are searched, which expression is characteristic for this syndrome. The differentiation of clinical outcome in patients with overlap syndrome compared with patients with either asthma or COPD is underlined. Perhaps the overlap syndrome should be considered as a new COPD phenotype.

Key words: asthma, COPD, overlap syndrome