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Pol. Merkur. Lek (Pol. Med. J.), 2012, XXXII/191: 293-297 Maximize

Pol. Merkur. Lek (Pol. Med. J.), 2012, XXXII/191: 293-297

Title: Early invasive strategy in patients with myocardial infarction and intraventricular conduction disturbances and plasma B-type natriuretic peptide levels assessed 6 months after myocardial infarction

Authors: iuraszkiewicz K., Sielski J., Janion-Sadowska A., Sadowski M., Janion M.

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SUMMARY IN POLISH & ENGLISH. FULL ARTICLE ONLY IN POLISH.

Early invasive strategy in patients with myocardial infarction and intraventricular conduction disturbances and plasma B-type natriuretic peptide levels assessed 6 months after myocardial infarction


Ciuraszkiewicz K.1, Sielski J.1,2, Janion-Sadowska A.1, Sadowski M.1, Janion M.1,2

1Department of Cardiology, Swietokrzyski Center of Cardiology Kielce, Poland; 2Faculty of Health Studies, University of Jan Kochanowski, Kielce, Poland

The aim of the study was to assess plasma B-type natriuretic peptide (BNP) levels in patients after myocardial infarction (MI) with intraventricular conduction defects (IVCD) and to define relationship between BNP level, treatment strategy and left ventricular performance.
Material and methods
. Four types of IVCD were noted: left bundle branch block (LBBB), right bundle branch block (RBBB), left anterior hemiblock (LAH) and left posterior hemiblock (LPH). A total of 158 patients six months after MI treated either invasively or conservatively were included. Of them 126 had IVCD (group A): LBBB-31, RBBB-36, LAH-l30, LPH-29, whereas 32 patients without IVCD served as controls (group B). Plasma BNP levels were measured using an immunoenzymatic method. All subjects underwent echocardiography to evaluate left ventricular function.
Results
. In group A significantly lower plasma BNP levels (186.3 vs 355.3 pg/mL; p
Conclusions. Invasive strategy in MI with IVCD, especially with LBBB, correlates with lower plasma BNP levels six months after index procedure. In patients with IVCD post MI plasma BNP level is better marker of dysfunction of the left ventricle than its ejection fraction.

Key words: early invasive strategy, myocardial infarction, intraventricular conduction defects, BNP

Pol. Merk. Lek., 2012, XXXII, 191, 293