Int. Rev. Allergol. Clin. Immunol. Family Med., 2015, XXI/2: 086-091 Maximize

Int. Rev. Allergol. Clin. Immunol. Family Med., 2015, XXI/2: 086-091

Title: Exercise-induced asthma – the problem still valid 

Authors: Radzik-Zając J, Wolańczyk-Mędrala A, Mędrala W. 

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Exercise-induced asthma – the problem still valid

Radzik-Zając J, Wolańczyk-Mędrala A, Mędrala W.

Chair and Department of Internal Diseases, Geriatry and Allergology, Medical University of Wrocław, Poland

Int. Rev. Allergol. Clin. Immunol. Family Med., 2015; Vol. 21, No. 2, 86

Physical activity might provoke the occurrence of asthma symptoms in asthmatics. Symptoms of bronchospasm like shortness of breath or wheezing that appear after exertion or during physical activity may indicate the presence of exercise-induced bronchoconstriction. The exercise-induced bronchoconstriction or as a synonym exercise-induced asthma are called as transient narrowing of the lower airway usually following after physical activity and they may be diagnosed regardless of the presence of bronchial asthma. The deterioration of lung function parameters (FEV1, PEF) after exercise is the criterion for diagnosis. The pathogenesis of exercise-induced bronchospasm has not been clearly established however there are two hypotheses (osmotic theory and vascular theory) that explain this phenomenon. Several studies have suggested an important role of eicosanoids (cysteinyl leukotrienes and prostaglandin D2) and gel-forming mucins in the pathogenesis of exercise-induced bronchoconstriction. There are methods of prevention e.g. warmup before exercise, mask covering athletes mouth used in the performance of effort at low ambient temperatures. Basic goal of pharmacological treatment is achievement of full asthma controlelimination of any symptoms including normal tolerance of exercise. In the case of exercise-induced bronchospasm inhaled short beta- 2 agonist is a drug of the choice. Particularly important is the correct diagnosis and treatment of exercise-induced asthma in athletes.

Key words: exercise-induced asthma, exercise-induced bronchoconstriction, athletes