Pol. Merkur. Lek (Pol. Med. J.), 2015, XXXIX/234: 364-367 Maximize

Pol. Merkur. Lek (Pol. Med. J.), 2015, XXXIX/234: 364-367

Title: Estimation of plasma 25(OH)D vitamin level in patients with metabolic syndrome 

Authors: Godala M, Materek-Kuśmierkiewicz I, Moczulski D, Szatko F, Gaszyńska E, Tokarski S, Kowalski J.

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Estimation of plasma 25(OH)D vitamin level in patients with metabolic syndrome

Godala M1, Materek-Kuśmierkiewicz I2, Moczulski D2, Szatko F3, Gaszyńska E3, Tokarski S4, Kowalski J5.

 Medical University of Lodz, Poland: 1Department of Hygiene of Nutrition and Epidemiology, 2Department of Internal Diseases and Nephrodiabetology, 3Department of Hygiene and Health Promotion, 5Department of Internal and Infectious Diseases; 4Faculty of Medicine, University of Rzeszow, Poland

Cardiovascular diseases are a major public health problem in developed and developing countries. A number of recent studies point to the pleiotropic differentiated effects of vitamin D, the deficiency of which positively correlates with the increased risk for cardiovascular diseases, hypertension, dyslipidemia, obesity or metabolic syndrome (MS). Vitamin D deficiency has also been proven to affect the progression of atherosclerosis.
The aim of this study
was to evaluate plasma 25(OH)D level in patients with MS.
Material and method
. The study included 268 patients with MS, 136 men and 132 women, aged 30-65 years (mean 59,62±9,21 years). The study group was divided according to the age and season. The concentration of 25-hydroxy vitamin D (25-OH-D) was assessed with the application of the LIAISON® test using chemiluminescent immunoassay (CLIA) technology.
. The mean plasma level of 25(OH)D was 14,56±7,81ng/ml in MS patients and it was not significantly higher in women than men (15,14 ±3,29ng/ml vs. 13,97±3,41 ng/ml, p>0,05). The lowest 25(OH)D concentration was noted in the oldest age group (9,24±4,78ng/ml). The highest 25(OH)D concentration was noted in summer months (23,71±3,82ng/ml).
. The concentration of vitamin D in the plasma of patients with MS was significantly lower than its recommendations. Age and season of the year were the factors strongly affecting the level of 25(OH)D in MS patients.

Key words: metabolic syndrome, vitamin D, seasonal variations

Pol Med J, 2015; XXXIX (234); 364–367